Find the detail you came for
Does TA1 on this site mean Thymosin Alpha 1?
Yes. TA1 is the short form used here for Oath’s Thymosin Alpha 1 listing. Thymalfasin is another name for the same linear, N-terminally acetylated 28-amino-acid polypeptide.
Where can I inspect the lot behind the TA1 listing?
The TA1 certificate page brings the batch field together with links to Oath’s certificate archive and the recorded batch PDF. Freedom Diagnostics was the laboratory named in the checked document.
How do the purity and endotoxin fields differ?
The certificate reported purity by HPLC-UV and an endotoxin screen by Limulus Amebocyte Lysate assay under USP <85>. Both endotoxin replicates passed. The test’s sensitivity did not describe a measured sample concentration or establish sterility.
Which amino-acid letters identify TA1?
Its 28-residue chain is written SDAAVDTSSEITTKDLKEKKEVVEEAEN. N-terminal acetylation is part of the identity in addition to those residue letters.
What did the solvent-based structure experiment find?
An alpha-helical region at residues 14–26 and two double beta-turns near the N-terminus were reported in the 2011 in vitro solution-NMR study. The solvent was a trifluoroethanol/water mixture; relevance to other environments remained an open question.
Which signaling names appeared in the 2023 synthesis?
TLR-associated IRF3 and NF-kappaB signaling, together with cytokine-production changes, appeared in the 2023 synthesis covering immune-cell experiments and human viral-infection studies. That publication synthesized earlier investigations.
Did the two hepatitis B comparisons show a stronger response?
The 1996 randomized human comparison involving 33 participants found no significant difference from interferon alfa in complete response, defined by ALT normalization and HBV-DNA loss. The 2000 randomized human comparison involving 44 participants reported no increase in combined biochemical and virological response and no HBsAg-negative participant. Both examined anti-HBe-positive, HBV-DNA-positive chronic hepatitis B.
Why do ETASS and TESTS need separate readings?
In the 2013 randomized human ETASS severe-sepsis study, monocyte HLA-DR improved more with thymosin alpha 1 on days 3 and 7. The 2025 double-blind, placebo-controlled human TESTS sepsis study found no significant difference in 28-day mortality among 1089 analyzed participants. The full comparison preserves the endpoints and analyses.
What remained uncertain in the human safety record?
Rare adverse events and long-term toxicity remained unresolved. Investigators in the 2013 human ETASS trial attributed no serious adverse event to thymosin alpha 1; the 2025 double-blind human TESTS trial found no statistically significant difference in assessed safety outcomes versus placebo. Those observations stayed limited to their studies.
Do the published papers establish the properties of an Oath vial?
The cited human investigations did not study this Oath batch, and equivalence with the research material remained unresolved. The batch document addressed its reported assays. The literature account also explains the solvent and statistical limits in the wider evidence.
How are the two store codes entered?
Copy SUPER for 20% off a first order or SUPER15 for 15% off any order, then enter the selected code at Oath checkout. The product buttons lead to the Thymosin Alpha 1 listing at oathresearch.com.
What shipping area and dispatch schedule does Oath state?
Oath ships within the United States. Orders placed before 12:00 p.m. MST, Monday–Friday, are dispatched the same business day, excluding federal holidays. Later orders, weekends and holidays move to the next business day. Most orders use 2-day business air; carrier transit time is separate from dispatch.
